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Department of Chemistry & Biochemistry
Green Research Group ACS Publication
Identifying drugs that can cross the blood brain barrier is a significant challenge for treating diseases of the central nervous system. The Green Group has shown that decorating molecules with an indole group can make their macrocycles permeable to the blood brain barrier - a necessity for drugs targeting Alzheimer's disease. The new molecules activate intracellular mechanisms that protect the cells from the oxidative stress that is known to cause neurodegenerative diseases. The work was completed by four undergraduate students, two graduate students, and one postdoctoral scholar in collaboration with the Akkaraju group. https://pubs.acs.org/doi/10.1021/acschemneuro.4c00530
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Our goal is for every student in the Department of Chemistry and Biochemistry to have hands-on experience in cutting-edge chemical research, as well as opportunities to interact with leading researchers across the discipline. Your donation to the Neilson, Minter, or Ruth Evelyn Sanders funds can help support these goals. Donations of any size are appreciated. Donations of $4000 or above to the Neilson or Minter funds can typically support a single undergraduate research experience. Donations of $500 or above to the Sanders fund can support bringing a nationally recognized researcher to visit TCU.
To donate, click here to visit TCU Giving and under “Gift Information”, select “Other – User Input Text” and enter Dr. Rob Neilson Chemistry Fund, Dr. David Minter Chemistry Research Endowment, or Sanders Chemistry Lectureship for your gift designation in the comment box. You can also give your gift in honor of/memory of a chemistry professor that had an impact on your life.